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The domain topogen.com states the following, "Topoisomerase I In Vivo Link Kit." I observed that the website also stated " Link Kit offers a very powerful method to deduce whether a given drug actually affects its predicted topo target in a given cancer cell in vivo." They also stated " One can quantify the activity of topoisomerase enzyme in vivo with this kit. Topo I Assay Quickstart How to get the assay properly validated and established in my lab? Latest Google Scholar Results. Complete listing of the latest Google Scholar results that reference the use of TopoGEN Products." The meta header had topoisomerase as the first keyword. This keyword was followed by topoisomerase screening, topoisomerase drug testing, and antibodies which isn't as urgent as topoisomerase. The other words the site used was gyrase. topoisomerase assay is also included but might not be seen by web crawlers.